Michelakis, Evangelos : rechercher sur Z-Library

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1

A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation

Sutendra, Gopinath, Kinnaird, Adam, Dromparis, Peter, Paulin, Roxane, Stenson, Trevor H., Haromy, Alois, Hashimoto, Kyoko, Zhang, Nancy, Flaim, Eric, Michelakis, Evangelos D.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 4.08 MB

english, 2014

2

Sirtuin 3 Deficiency Is Associated with Inhibited Mitochondrial Function and Pulmonary Arterial Hypertension in Rodents and Humans

Paulin, Roxane, Dromparis, Peter, Sutendra, Gopinath, Gurtu, Vikram, Zervopoulos, Sotirios, Bowers, Lyndsay, Haromy, Alois, Webster, Linda, Provencher, Steeve, Bonnet, Sebastien, Michelakis, Evangelos

Journal:

Cell Metabolism

Année:

2014

Langue:

english

Fichier:

PDF, 3.79 MB

english, 2014

3

Acute Hemodynamic Effects of Single-Dose Sildenafil When Added to Established Bosentan Therapy in Patients With Pulmonary Arterial Hypertension: Results of the COMPASS-1 Study

Gruenig, Ekkehard, Michelakis, Evangelos, Vachiéry, Jean-Luc, Vizza, Carmine Dario, Meyer, F. Joachim, Doelberg, Martin, Bach, Doris, Dingemanse, Jasper, Galiè, Nazzareno

Journal:

Journal of Clinical Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 252 KB

english, 2009

4

Metabolic control of epigenetics in cancer

Kinnaird, Adam, Zhao, Steven, Wellen, Kathryn E., Michelakis, Evangelos D.

Journal:

Nature Reviews Cancer

Année:

2016

Langue:

english

Fichier:

PDF, 583 KB

english, 2016

5

Calcium channels in smooth muscle cells from cerebral precapillary arterioles activate at more negative potentials than those from basilar artery

Evangelos Michelakis, Kirti Tewari, J. Marc Simard

Journal:

Pflügers Archiv European Journal of Physiology

Année:

1994

Langue:

english

Fichier:

PDF, 323 KB

english, 1994

6

The role of mitochondria in pulmonary vascular remodeling

Peter Dromparis, Gopinath Sutendra, Evangelos D. Michelakis

Journal:

Journal of Molecular Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 513 KB

english, 2010

7

Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension

Gopinath Sutendra, Peter Dromparis, Sébastien Bonnet, Alois Haromy, Michael S. McMurtry, R. Chris Bleackley, Evangelos D. Michelakis

Journal:

Journal of Molecular Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2011

8

The Role of the NO Axis and its Therapeutic Implications in Pulmonary Arterial Hypertension

Evangelos D. Michelakis

Journal:

Heart Failure Reviews

Année:

2003

Langue:

english

Fichier:

PDF, 446 KB

english, 2003

9

The Role of K+ Channels in Determining Pulmonary Vascular Tone, Oxygen Sensing, Cell Proliferation, and Apoptosis: Implications in Hypoxic Pulmonary Vasoconstriction and Pulmonary Arterial Hypertension

ROHIT MOUDGIL, EVANGELOS D. MICHELAKIS, STEPHEN L. ARCHER

Journal:

Microcirculation

Année:

2006

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2006

10

A dynamic and chamber-specific mitochondrial remodeling in right ventricular hypertrophy can be therapeutically targeted

Jayan Nagendran, Vikram Gurtu, David Z. Fu, Jason R.B. Dyck, Al Haromy, David B. Ross, Ivan M. Rebeyka, Evangelos D. Michelakis

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Année:

2008

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2008

11

Anorectic drugs and vascular disease:: The role of voltage-gated K+ channels

Evangelos Michelakis

Journal:

Vascular Pharmacology

Année:

2002

Langue:

english

Fichier:

PDF, 249 KB

english, 2002

12

Phosphodiesterase Type 5 Inhibitors for Pulmonary Arterial Hypertension

Archer, Stephen L., Michelakis, Evangelos D.

Journal:

Boston Medical and Surgical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 543 KB

english, 2009

13

Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells

Evangelos D. Michelakis, Bernard Thébaud, E. Kenneth Weir, Stephen L. Archer

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2004

Langue:

english

Fichier:

PDF, 831 KB

english, 2004

14

Diversity of mitochondria in vascular oxygen sensing

Evangelos Michelakis, Stephen Archer

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2001

Langue:

english

Fichier:

PDF, 137 KB

english, 2001

15

A pulmonary vascular redox O2 sensor

Stephen Archer, Evangelos Michelakis

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2001

Langue:

english

Fichier:

PDF, 150 KB

english, 2001

16

The opposing effects of hypoxia on pulmonary versus renal arteries are regulated by a mitochondria-based O2 sensor

Evangelos Michelakis, Ali Nsair, Xsi-Cheng Wu, Kyoko Hashimoto, Stephen Archer

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2001

Langue:

english

Fichier:

PDF, 171 KB

english, 2001

17

The proximal mitochondrial electron transport chain regulates O2 sensing in the human ductus arteriosus

Bernard Thebaut, Evangelos Michelakis, Ali Nsair, Ivan Rebeyka

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2001

Langue:

english

Fichier:

PDF, 126 KB

english, 2001

18

Voltage-gated potassium channels in human ductus arteriosus

Evangelos Michelakis, Ivan Rebeyka, Jane Bateson, Peter Olley, Lakshmi Puttagunta, Stephen Archer

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 197 KB

english, 2000

19

Mitochondria in Vascular Health and Disease

Dromparis, Peter, Michelakis, Evangelos D.

Journal:

Annual Review of Physiology

Année:

2013

Langue:

english

Fichier:

PDF, 1.80 MB

english, 2013

20

G-protein-coupled receptors and pulmonary arterial hypertension (PAH)

Roxane Paulin, Evangelos Michelakis

Journal:

Drug Discovery Today: Disease Models

Année:

2012

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2012

21

297 DICHLOROACETATE IS A NOVEL THERAPY FOR RENAL CELL CARCINOMA

Kinnaird, Adam, Dromparis, Peter, Haromy, Alois, Bowers, Lyndsay, Hashimoto, Kyoko, Sutendra, Gopinath, Michelakis, Evangelos

Journal:

The Journal of Urology

Année:

2012

Langue:

english

Fichier:

PDF, 59 KB

english, 2012

22

Inflammation, Growth Factors, and Pulmonary Vascular Remodeling

Paul M. Hassoun, Luc Mouthon, Joan A. Barberà, Saadia Eddahibi, Sonia C. Flores, Friedrich Grimminger, Peter Lloyd Jones, Michael L. Maitland, Evangelos D. Michelakis, Nicholas W. Morrell, John H. New

Journal:

Journal of the American College of Cardiology

Année:

2009

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2009

23

Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension

Evangelos D. Michelakis, Wayne Tymchak, Dale Lien, Linda DaSilva, Kyoko Hashimoto, Stephen L. Archer

Journal:

Journal of the American College of Cardiology

Année:

2002

Langue:

english

Fichier:

PDF, 163 KB

english, 2002

24

Relevant Issues in the Pathology and Pathobiology of Pulmonary Hypertension

Tuder, Rubin M., Archer, Stephen L., Dorfmüller, Peter, Erzurum, Serpil C., Guignabert, Christophe, Michelakis, Evangelos, Rabinovitch, Marlene, Schermuly, Ralph, Stenmark, Kurt R., Morrell, Nicholas

Journal:

Journal of the American College of Cardiology

Année:

2013

Langue:

english

Fichier:

PDF, 602 KB

english, 2013

25

Reduced native right ventricular T1in Anderson-Fabry disease as compared to patients with pulmonary hypertension

Pagano, Joseph J, Chow, Kelvin, Khan, Aneal, Michelakis, Evangelos, Paterson, Ian, Oudit, Gavin Y, Thompson, Richard B

Journal:

Journal of Cardiovascular Magnetic Resonance

Année:

2014

Langue:

english

Fichier:

PDF, 269 KB

english, 2014

26

Pioglitazone inhibits HIF-1α-dependent angiogenesis in rats by paracrine and direct effects on endothelial cells

Dromparis, Peter, Sutendra, Gopinath, Paulin, Roxane, Proctor, Spencer, Michelakis, Evangelos D., McMurtry, M. Sean

Journal:

Journal of Molecular Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 827 KB

english, 2014

27

THE PATHOBIOLOGY OF PULMONARY HYPERTENSION

Michelakis, Evangelos D., Weir, E. Kenneth

Journal:

Clinics in Chest Medicine

Année:

2001

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2001

28

The Metabolic Basis of Pulmonary Arterial Hypertension

Sutendra, Gopinath, Michelakis, Evangelos D.

Journal:

Cell Metabolism

Année:

2014

Langue:

english

Fichier:

PDF, 3.03 MB

english, 2014

29

O2Sensing Is Preserved in Mice Lacking the gp91 Phox Subunit of NADPH Oxidase

Stephen L. Archer, Helen L. Reeve, Evangelos Michelakis, Lakshmi Puttagunta, Ross Waite, Daniel P. Nelson, Mary C. Dinauer and E. Kenneth Weir

Journal:

Proceedings of the National Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 1.32 MB

english, 1999

30

Riociguat for HF with Pulmonary Hypertension (PH): Post-hoc Analysis of LEPHT by Baseline Pulmonary Vascular Resistance (PVR) and Pulmonary Vascular Gradient (PVG)

Bonderman, Diana, Ghio, Stefano, Felix, Stephan B., Ghofrani, Hossein-Ardeschir, Michelakis, Evangelos, Mitrovic, Veselin, Oudiz, Ronald J., Boateng, Francis, Roessig, Lothar, Semigran, Marc J.

Journal:

Journal of Cardiac Failure

Année:

2014

Langue:

english

Fichier:

PDF, 127 KB

english, 2014

31

New insights for the diagnosis and management of right ventricular failure, from molecular imaging to targeted right ventricular therapy

Haddad, Francois, Ashley, Euan, Michelakis, Evangelos D

Journal:

Current Opinion in Cardiology

Année:

2010

Langue:

english

Fichier:

PDF, 442 KB

english, 2010

32

Left ventricular systolic dysfunction associated with pulmonary hypertension riociguat trial (LEPHT): rationale and design

Ghio, Stefano, Bonderman, Diana, Felix, Stephan B., Ghofrani, Hossein A., Michelakis, Evangelos D., Mitrovic, Veselin, Oudiz, Ronald J., Frey, Reiner, Roessig, Lothar, Semigran, Marc J.

Journal:

European Journal of Heart Failure

Année:

2012

Langue:

english

Fichier:

PDF, 290 KB

english, 2012

33

Metabolic modulation of cancer: a new frontier with great translational potential

Kinnaird, Adam, Michelakis, Evangelos D.

Journal:

Journal of Molecular Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2015

34

A phase I open-labeled, single-arm, dose-escalation, study of dichloroacetate (DCA) in patients with advanced solid tumors

Chu, Quincy Siu-Chung, Sangha, Randeep, Spratlin, Jennifer, J. Vos, Larissa, Mackey, John R., McEwan, Alexander J. B., Venner, Peter, Michelakis, Evangelos D.

Journal:

Investigational New Drugs

Année:

2015

Langue:

english

Fichier:

PDF, 475 KB

english, 2015

35

Critical Role of the Axonal Guidance Cue EphrinB2 in Lung Growth, Angiogenesis, and Repair

Vadivel, Arul, van Haaften, Tim, Alphonse, Rajesh S., Rey-Parra, Gloria-Juliana, Ionescu, Lavinia, Haromy, Al, Eaton, Farah, Michelakis, Evangelos, Thébaud, Bernard

Journal:

American Journal of Respiratory and Critical Care Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 2.29 MB

english, 2012

36

Emerging Therapies and Future Directions in Pulmonary Arterial Hypertension

Gurtu, Vikram, Michelakis, Evangelos D.

Journal:

Canadian Journal of Cardiology

Année:

2015

Langue:

english

Fichier:

PDF, 2.11 MB

english, 2015

37

Use of Sildenafil for Safe Improvement of Erectile Function and Quality of Life in Men With New York Heart Association Classes II and III Congestive Heart Failure

Webster, Linda J., Michelakis, Evangelos D., Davis, Terry, Archer, Stephen L.

Journal:

Archives of Internal Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 111 KB

english, 2004

38

Updating clinical endpoint definitions

Hassoun, PaulM, Nikkho, Sylvia, Rosenzweig, ErikaB, Moreschi, Gail, Lawrence, John, Teeter, John, Meier, Christian, Ghofrani, ArdeshirH, Minai, Omar, Rinaldi, Paula, Michelakis, Evangelos, Oudiz, Rona

Journal:

Pulmonary Circulation

Année:

2013

Langue:

english

Fichier:

PDF, 763 KB

english, 2013

39

Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology

Sutendra, Gopinath, Michelakis, Evangelos D.

Journal:

Frontiers in Oncology

Année:

2013

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2013

40

Developmental Absence of the O2 Sensitivity of L-Type Calcium Channels in Preterm Ductus Arteriosus Smooth Muscle Cells Impairs O2 Constriction Contributing to Patent Ductus Arteriosus

Thébaud, Bernard, Wu, Xi-Chen, Kajimoto, Hidemi, Bonnet, Sandra, Hashimoto, Kyoko, Michelakis, Evangelos D, Archer, Stephen L

Journal:

Pediatric Research

Année:

2008

Fichier:

PDF, 699 KB

2008

41

Developmental Absence of the O2 Sensitivity of L-Type Calcium Channels in Preterm Ductus Arteriosus Smooth Muscle Cells Impairs O2 Constriction Contributing to Patent Ductus Arteriosus

Thébaud, Bernard, Wu, Xi-Chen, Kajimoto, Hidemi, Bonnet, Sandra, Hashimoto, Kyoko, Michelakis, Evangelos D, Archer, Stephen L

Journal:

Pediatric Research

Année:

2008

Langue:

english

Fichier:

PDF, 699 KB

english, 2008

42

Sildenafil Reverses O2 Constriction of the Rabbit Ductus Arteriosus by Inhibiting Type 5 Phosphodiesterase and Activating BKCa Channels

Thébaud, Bernard, Michelakis, Evangelos, Wu, Xi-Chen, Harry, Gwyneth, Hashimoto, Kyoko, Archer, Stephen L

Journal:

Pediatric Research

Année:

2002

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2002

43

The Role of Doppler Echocardiography in Pulmonary Artery Hypertension

Paterson, Ian, Michelakis, Evangelos D.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 944 KB

english, 2011

44

Pulmonary Vasoconstriction, Oxygen Sensing, and the Role of Ion Channels

Weir, E. Kenneth, Reeve, Helen L., Peterson, Douglas A., Michelakis, Evangelos D., Nelson, Daniel P., Archer, Stephen L.

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 3.38 MB

english, 1998

45

Cell-Based Gene Therapy in Pulmonary Arterial Hypertension: Table.

Gurtu, Vikram, Michelakis, Evangelos

Journal:

Circulation Research

Année:

2015

Langue:

english

Fichier:

PDF, 470 KB

english, 2015

46

A Global Pulmonary Arterial Hypertension Registry: Is It Needed? Is It Feasible?

Gomberg-Maitland, Mardi, Michelakis, Evangelos D.

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 330 KB

english, 2010

47

PD33-11 METABOLIC MODULATION WITH DICHLOROACETATE REVERSES THE WARBURG EFFECT AND REDUCES THE GROWTH OF CLEAR CELL RENAL CELL CARCINOMA IN VITRO AND IN VIVO

Kinnaird, Adam, Dromparis, Peter, Paulin, Roxane, Saleme, Bruno, Stenson, Trevor, Pink, Desmond, Lewis, John, Michelakis, Evangelos

Journal:

The Journal of Urology

Année:

2015

Langue:

english

Fichier:

PDF, 41 KB

english, 2015

48

ACUTE HEMODYNAMIC EFFECT OF SILDENAFIL IN COMPARISON WITH INHALED NITRIC OXIDE IN PATIENTS RECEIVING BOSENTAN THERAPY FOR PULMONARY ARTERIAL HYPERTENSION

Galie, Nazzareno, Michelakis, Evangelos, Vachiery, Jean-Luc, Vizza, Carmine Dario, Meyer, F.J., Gruenig, Ekkehard

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 209 KB

english, 2007

49

MP85-01 MYOCYTE ENHANCER FACTOR 2A (MEF2A) IS UP-REGULATED IN CLEAR CELL RENAL CELL CARCINOMA

Kinnaird, Adam, Saleme, Bruno, Gurtu, Vikram, Zervopoulos, Sotirios, Boukouris, Aristeidis, Haromy, Alois, Stenson, Trevor, Watson, Kristalee, Dromparis, Peter, Michelakis, Evangelos

Journal:

The Journal of Urology

Année:

2016

Langue:

english

Fichier:

PDF, 37 KB

english, 2016

50

F2-Isoprostanes

Dromparis, Peter, Michelakis, Evangelos D.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1020 KB

english, 2012